November 16th Celebration of our 10 year Anniversary with Bill Faloon and Max More

Enjoy our 10 Year Anniversary Celebration with presentations by Bill Faloon and Max More. This year marks 10 years since the founding of The Church of Perpetual Life. Our Co-Founder Bill Faloon will give a presentation commemorating our “Ten Year History,” taking us through the years of our amazing growth and international recognition. Q & A with Bill after the presentation. Max More presents “Cryonics as Plan A” about the importance of signing up for cryonics before it is too late! And also about building muscle mass for health with resistance training.

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Summary:

In the Perpetual Life 10 Year Anniversary Celebration YouTube video, Bill Faloon and Max More discuss the advancements and potential solutions for reversing aging. They expressed their gratitude for the Church of Perpetual Life community’s progress in facilitating connections and events, including the annual Radical Life Extension Festival. Bill Faloon shared the origins of the church and its growth over the past decade, starting with humble beginnings and expanding to a larger venue due to growing interest. They also discussed ongoing research into using drugs like Rapa and clinical trials in Singapore to extend healthy human lifespans. The speakers touched on recent discoveries, such as extending telomeres in rats, manipulating genes Sir2 and Hap4 in yeast cells to extend their lifespan, and rejuvenating old mice using Yamanaka transcription factors. They encouraged healthy lifestyle choices and ongoing research for making age reversal a reality. The conversation included discussions on various books and research, the potential benefits of red meat, and the importance of addressing stress and preventing sarcopenea. Bill Faloon shared his concerns about the impact of processed foods, while Max More emphasized their skepticism about the negative portrayal of red meat. They also discussed practical applications like metformin, senescent cells, and the importance of developing new pharmaceuticals to improve the fight against aging. Longevity enthusiasts contributed to the conversation, sharing their experiences and supporting continued research. Overall, the speakers emphasized the importance of staying informed, maintaining healthy habits, and dedicating resources to research and development to expand both the quality and quantity of life

• 00:00:00 In this section of the Perpetual Life 10 Year Anniversary Celebration video, Bill Faloon and Max More welcome attendees to the event, celebrating both Thanksgiving and the Church’s 10th anniversary. The Creed of the Church of Perpetual Life is presented, focusing on the goal of striving for an unlimited lifespan and creating a haven for achieving eternal life. The hosts also remind the audience that this is a transhuman church, not a bible-based one. Bill Faloon shares humorous anecdotes from the Church’s history, including encountering chickens without heads, meeting a potential large donor who became intoxicated and then disappeared, and other unusual occurrences
• 00:05:00 In this section of the YouTube video, the speakers reflect on the importance of the Church of Perpetual Life community in facilitating connections and events, including the annual Radical Life Extension Festival. They also express gratitude for the founding of the church ten years prior, which started with humble beginnings but quickly grew due to its unique concept. Bill Faloon, one of the church’s founders, shares how he came up with the idea with the help of Aubrey De Grey and faced initial skepticism. The community has grown significantly, and the Church in Hollywood could no longer accommodate everyone attending its services
• 00:10:00 In this section, Bill Faloon discusses the formation of the Church of Perpetual Life ten years ago. The idea originated from Neil Vanderee, who lived on the west coast of Florida. Faloon and Vander founded the church after meeting at a scientific conference. The first church in Hollywood was too small and lacked enough parking space, so they moved to a larger one with 132,000 square feet and adequate parking. The property also includes a separate school building, converted into living facilities for visitors. The church has hosted notable speakers, including Aubrey de Grey, Martine Rothblatt, and Liz Parish, in its free events. When the church was founded in 2013, the prospect of reversing aging was uncertain, but within a few years, Technology developments and increased media coverage brought the possibility closer to reality. The church’s monthly meetings and discussions on living forever have contributed to the media’s positive coverage, reaching millions of influential people via publications like The Economist
• 00:15:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” YouTube video, Bill Faloon and Max More discuss the hot topic of living longer and indefinitely, which gained mainstream attention with the September 2023 issue of The Economist. They mention scientific research exploring human capabilities to live indefinitely, including treatments like young blood transfusions and purging harmful cells. These approaches, along with cellular reprogramming and calorie restriction, aim to slow down aging. The speakers also emphasized healthier lifestyle choices and avoiding unhealthy habits like processed foods and smoking, echoing a recent JP Morgan Chase wealth management seminar’s emphasis on understanding the body as an investment and making good choices to boost longevity. The speakers, who are Williams O’Flaherty and Kara Dubnowski, also touched on the importance of aggressive testing and preventative medicine in extending healthy lifespans. Singapore is also making strides in this field, leading research on new longevity technologies at a Healthy Aging Clinic in a prestigious university hospital
• 00:20:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon discusses ongoing research into extending healthy human lifespans through drugs like Rapa and clinical trials at the University Hospital in Singapore with funding from the Saudi Arabian Evolution Fund. The scientific community is increasingly acknowledging the potential for defeating aging, as seen in mainstream publications like National Geographic. Major investments are being made in longevity research, and the FDA has approved studies related to transhumanism and brain-computer implants. Montenegro changes regulations to accelerate the development of longevity drugs as people become more interested in investing in their health for potential immortality. The founder of Chad GPT, a 30-something tech entrepreneur, has put up $180 million to conquer death, with a prediction of a life-extending pill on the horizon
• 00:25:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon and Max More discuss various books and research related to aging and potential solutions for extending lifespan. Bill Faloon mentions a book called “Outlive and Again” by Peter Attia, which focuses on preventing premature death and includes information about apolipoprotein B and its connection to heart attacks. Attia’s book made it to the number one spot on the New York Times bestseller list in 2023. Mark Heyman, a doctor they have worked with, also wrote a book called “Young Forever” that reached the top of the New York Times list as well. The conversation then shifts to telomeres, which are connected to the risk of diseases such as heart attacks and infections. Research from 2003 showed that extending the telomeres in rats increased their maximum lifespan. Now, people are using young plasma to potentially rejuvenate older individuals. However, regulatory issues, such as the FDA not recognizing aging as a disease, are holding back significant funding for research. Mainstream media, including the Wall Street Journal and Financial Times, have started reporting on reversing aging and the search for drugs to delay or reverse biological aging. A potential drug for reversing aging could represent the greatest discovery since the advent of antibiotics. The attention and publicity surrounding this field increased after the founding of an organization (implied to be the Perpetual Life Church) in 2013, which has led to media coverage and scientific interest. Wired Magazine reported that a potential anti-aging drug may be available before the end of the year, with cytic type therapies being one of the possibilities. The opportunities to address aging, which was a leading cause of death in the early 1900s alongside diseases like tuberculosis and diarrhea, are now in our reach
• 00:30:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon and Max More discuss recent advancements in research aimed at reversing aging and extending lifespan. An extensive article covered in Medscape, a website read by conventional doctors, advocates for doctors to identify age-related problems using biomarkers and intervene to reverse or slow aging. One significant discovery from 2022 involved manipulating genes Sir2 and Hap4 in yeast cells, resulting in a 105% extension of their lifespan. This discovery, published in Science magazine, could potentially be translated into human application. Additionally, in 2022, researchers were able to rejuvenate old mice using Yamanaka transcription factors, making their skin appear younger and reducing inflammation and senescent cells, but data on their extended lifespan is yet to be collected
• 00:35:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon and Max More discuss recent scientific studies on reversing aging in mice using Yamanaka transcription factors. The studies showed improvements in epigenetic markers and restored youthful functionality, but none reported extended lifespan. A third study, published in January 2023, was able to extend the remaining lifespan of mice by 109% using the same approach. The researchers expressed Yamanaka factors using an adeno-associated virus and controlled their activity with toxy cycling. The longer the Yamanaka factors were expressed, the better the results. This study offers hope for extending human lifespan and potentially living in an era where age reversal is routine. The speakers also emphasize the importance of healthy habits, such as an optimized diet, which can add years to your lifespan. The presentation ended with a call to action for continued research and dedication to making age reversal a reality. [Applause
• 00:40:00 In this section of the Perpetual Life 10 Year Anniversary Celebration YouTube video, Bill Faloon and Max More discuss various aspects of aging and potential methods to reverse it. Faloon shares his concerns about the impact of bad food on health, particularly processed foods, and mentions that some practitioners are experimenting with Yamanaka factors to reverse aging in animals. He also recounts the story of a medical doctor from the past who intentionally infected himself with diseases to better understand their progression. Max More responds to Faloon’s discussion on diet, expressing skepticism about the negative portrayal of red meat and suggesting that it is actually beneficial when considering its nutritional profile. He also shares his personal experience of reducing his red meat intake to maintain better health
• 00:45:00 In this section of the Perpetual Life 10 Year Anniversary Celebration video, Bill Faloon and Max More discuss various topics related to health and aging. They answer a question about sources for obtaining Rapa, a substance that is believed to have anti-aging properties, and recommend purchasing it from offshore pharmacies due to its affordability. Max More emphasizes the significance of acknowledging stress as a major negative impact on human health and encourages everyone to monitor their blood pressure. He suggests taking Rapamycin once a week in a high dose to initiate beneficial autophagy and clear cellular debris, with no reported significant side effects for most people. The conversation also touches on the possibility of reaching a longevity escape velocity by 2029 or 2030 as forecasted by Ray Kurzweil, with hopes for significant human aging reversal advancements driving rapid scientific progress
• 00:50:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon and Max More discuss various methods and technologies to potentially reverse or control aging. Sky asks about practical applications like metformin, an off-label prescription drug that helps control blood sugar and has been shown to extend lifespan. Berberine is mentioned as an alternative for those unable to access metformin. The discussion also covers senescent cells and potential pharmaceutical solutions such as danab and cortin. New pharmaceuticals are being investigated and will be recommended once research is validated. Methionine restriction in relation to meat consumption is addressed, and the importance of exercise and weight-bearing activity to prevent sarcopenia is emphasized. Longevity enthusiast Larry expresses gratitude for their work and contributes to the conversation about the importance of extending both the quality and quantity of life by helping others. The discussion concludes with Pat asking about supplements to reduce senescent cell activity, to which it is mentioned that nutritional formulations containing flavens and cortin can be used to try and induce cellular regeneration
• 00:55:00 In this section of the YouTube video titled “Perpetual Life 10 Year Anniversary Celebration!”, Bill Faloon discusses the benefits of resveratrol, a compound found in grapes and red wine, which has mechanistic similarities to senolytics and may help inhibit the production of B cell lymphoma, a major risk factor for older adults. He also mentions a new drug, yet to be introduced, which may be safer and more effective than resveratrol. When asked about a published list of recommended vitamins and doses, Faloon explains that while they have been recommending supplements for over 40 years, there is not enough science to definitively establish optimal dosages. He also mentioned ongoing studies in Singapore focusing on supplements and doses to validate their effectiveness. Faloon also fields questions about specific health conditions, such as ALS, for which they are hearing promising results but have not yet validated, and about the impact of cortisol on the brain and potential ways to reduce its effects through nutrients like vitamin C, aspirin, and ashwagandha. A question about eating eggs resulted in the mention of conflicting research that suggests both no impact on longevity and increased risk of cancer with high consumption

01:00:00 – 01:50:00

In the “Perpetual Life 10 Year Anniversary Celebration” YouTube video, Bill Faloon and Max More discuss various aspects of anti-aging and longevity, including the egg controversy, benefits of suppressing mTOR, and neurodegenerative diseases like Parkinson’s. They also introduce cryonics as a potential solution for “true death” prevention and a backup plan for life extension. The speakers emphasize the importance of maintaining good health, the benefits of exercise and intermittent fasting, and affordable cryonic preservation options. They express optimism about the future of cryonic preservation and the restoration of electrical functions and memory. Upcoming events, including a remembrance ceremony and a Thanksgiving feast, were announced with an upbeat and inspirational song encouraging positivity and focusing on the present moment

• 01:00:00 In this section of the YouTube video titled “Perpetual Life 10 Year Anniversary Celebration,” Bill Faloon and Max More discuss various aspects of anti-aging and longevity, including the controversy surrounding eggs, the benefits of suppressing mTOR to extend lifespan, and potential solutions for neurodegenerative diseases like Parkinson’s. The egg debate was discussed with references to studies showing both the negative (red arrow down) and positive effects of egg consumption. Bill explained that while aging begins at birth, the objective is to keep cells biologically young by reversing aging through reprogramming, allowing one to remain in a young state while chronologically aging. Additionally, they discussed the role of mTOR in accelerating aging and making individuals more vulnerable to cancer. Calorie restriction and intermittent fasting were suggested as ways to suppress mTOR, while Rapamycin (Rapy) was discussed as a drug that has shown effectiveness in animal studies by extending lifespan and improving health. Lastly, they touched upon potential breakthroughs in treating neurodegenerative diseases such as Alzheimer’s and Parkinson’s with healthy young plasma, or exosomes from stem cells, which may help regenerate cells
• 01:05:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” YouTube video, Bill Faloon shares insights about potential treatments for neurodegenerative diseases, specifically Parkinson’s disease. He discusses the use of Granulocyte Colony Stimulating Factor (G-CSF) in conjunction with young plasma to regenerate neurological function. Three independent doctors, including Dr. Maharaj in Boon Beach, have reported positive results in using this treatment. The process involves administering the drug for seven days followed by a seven-day break, measuring improvements in Parkinson’s symptoms. Bill Faloon expresses gratitude to his team members and introduces Max More, a transhumanist and founder of the Extropy Institute, who speaks about cryonics as a primary approach to life extension, preserving the body at extremely low temperatures as a backup plan
• 01:10:00 In this section of the Perpetual Life 10 Year Anniversary Celebration video, Bill Faloon and Max More discuss the concept of cryonics, which they describe as an extension of emergency medicine and a way to prevent “true death.” They explain that clinical death, or the cessation of heartbeat and respiration, is not the same as “true death,” and that advanced technology might one day be able to repair the damage caused by dying processes. They also introduce the idea of deep cold preservation as a means of halting these processes and potentially reviving individuals in the future when advanced repair methods become available
• 01:15:00 in this section of the YouTube video titled “Perpetual Life 10 Year Anniversary Celebration!”, Bill Faloon and Max More discuss the concepts of cryonics and longevity escape velocity. Cryonics is a process that preserves deceased bodies with the hope of reviving them in the future, and Eric Drexler’s book “Engines of Creation” is recommended for further understanding. Longevity escape velocity is the idea that new treatments will slow down the aging process, eventually allowing humans to stop aging and reverse it. The idea is inspired by the concept of reaching escape velocity to leave the Earth’s gravity well. While the goal is optimistic, it’s uncertain when this will happen, and there are various competing theories on what causes aging. The speaker also mentions recent global increases in life expectancy and the reversal of this trend in the United States due to the pandemic
• 01:20:00 In this section of the Perpetual Life 10 Year Anniversary Celebration video, Greg Lindsay shares an experiment where a group of people took a treatment believed to reverse aging, and after three months, they got more than a year younger based on biological aging tests. Researcher Steve Horvath, who tested the samples, suggested even greater improvements could be achieved with a longer trial period. Although the speaker expresses optimism about beating aging, he cautions against procrastinating cryonic arrangements due to the uncertainty of when biological immortality will be achieved. He emphasizes the importance of maintaining good health even with cryonic arrangements, as the better the condition one is in at the time of preservation, the greater the chances of successful revival. The speaker also explains that some degenerative diseases, such as ALS, offer a better chance of successful cybernetic preservation than sudden events like heart attacks. The speaker mentions a few organizations dedicated to extending human life, such as the Alcor Life Extension Foundation and the Cryonics Institute
• 01:25:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Max More discusses his perspective on life extension and cryonics, comparing it to a financial emergency fund. He suggests focusing on cryonic preservation first before exploring other potential life-extension methods. More also mentions the growing acceptance and positive press surrounding life extension and cryonics. Toward the end of the excerpt, he shifts the conversation to discuss the importance of strength training and resistance exercise for overall health and longevity. He emphasizes the role of resistance training in maintaining bone strength, muscle health, joint function, and independence in older age
• 01:30:00 In this section of the YouTube video titled “Perpetual Life 10 Year Anniversary Celebration!”, a woman shares her experience of staying active despite being paralyzed and the importance of exercise for health and longevity. She emphasizes the significance of maintaining muscles, bones, and joints through resistance exercise, which reduces the risk of various diseases such as diabetes, colon cancer, osteoporosis, and metabolic syndrome. The woman encourages making exercise a regular habit, sharing her personal experience of feeling better after forcing herself to go even when she doesn’t feel like it. Research indicates that just 30 to 60 minutes per week of resistance exercise, such as body weight exercises or using bands, can produce most of the benefits. The combination of both resistance and aerobic exercise is even more effective for longevity
• 01:35:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon and Max More discuss the benefits of exercise and intermittent fasting for longevity. They mention studies showing that modest exercise, such as two workouts a week, can yield significant outcomes. However, they caution that these studies were based on older individuals, and more intense exercise might not be suitable for everyone, especially those with limited fitness or advanced age. They also remind the audience that stress, including the stress induced by intense exercise and intermittent fasting, can be beneficial in the right doses. They recommend resistance training for maximum benefits, emphasizing that it’s not essential to commit excessive time or resources to achieve progress. Instead, one should focus on intensity and consistency. They add that the expression “what doesn’t kill me makes me stronger” applies to both exercise and fasting. Lastly, they mention their involvement in research on cryonic preservation and express confidence in its potential due to recent advancements. They encourage listeners to maintain a good fitness level to optimize the benefits of cryonic preservation. Max addresses questions about the cost of cryonic preservation, stating that costs vary depending on the organization one signs up with and the chosen options. Still, there are more affordable options available, like those offered by the Alcor Life Extension Foundation and the Cryonics Institute. Overall, their message revolves around the importance of a healthy lifestyle, including exercise, intermittent fasting, and considering cryonic preservation as an option for a long and healthy life
• 01:40:00 In this section, Bill Faloon and Max More discuss the costs and procedures involved in cryonic preservation at Alcor, a cryonics organization. Faloon provides two prices: $220,000 for whole-body preservation, which covers sending a team to the patient’s bedside, removing and replacing blood, and preventing ice formation; and $80,000 for brain-only preservation. The majority of these funds are put into a separate trust fund called the patient care trust fund, which can only be used for the continued cryonic preservation and eventual revival of the patient. Membership fees, which are a few hundred dollars per month, also apply. The process uses cryoprotectants to prevent ice formation and aims to preserve the structures that code for memory and personality. Although the restoration of electrical functions and memory is not fully understood, they are optimistic that the chemical activity will restart, preserving memories and personality. They have taken brain samples from research subjects, like Dr. Steven Co, and the results indicate that the structures are well-preserved
• 01:45:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, Bill Faloon and Max More discuss the potential of bringing people back to life and the need to solve the aging problem before doing so. Max Moore then announces upcoming events, including a remembrance ceremony and a Thanksgiving feast. The speakers emphasize the importance of unity, love, and respect, and urge attendees to continue striving for a better world. The music plays throughout the announcement, encouraging positivity and, looking forward to the future
• 01:50:00 In this section of the “Perpetual Life 10 Year Anniversary Celebration” video, an upbeat and inspirational song is played as an introduction to the speeches by Bill Faloon and Max More. The lyrics encourage listeners to focus on the present moment and appreciate it, instead of dwelling on the past or worrying about the future. The melody is catchy and repetitive, intended to leave a positive and motivational impact on the audience